Fmoc Solid Phase Peptide Synthesis: A Practical Approach by Peter D. White, W. C. Chan

Fmoc Solid Phase Peptide Synthesis: A Practical Approach



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Fmoc Solid Phase Peptide Synthesis: A Practical Approach Peter D. White, W. C. Chan ebook
Publisher: Oxford University Press, USA
Format: pdf
ISBN: 0199637249, 9780199637249
Page: 376


GO Fmoc Solid Phase Peptide Synthesis: A Practical Approach Author: Peter D. Fmoc Solid Phase Peptide Synthesis: A Practical Approach book download Peter D. This new approach offers significant advantages such as more simple utility, minimal side reactions, large scale synthesis of peptide drugs, and greater cost effectiveness. The chemical synthesis of small proteins has only recently become feasible with reliability. Language: English Released: 2000. In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. Automated solid-phase peptide synthesis coupled with optimized Fmoc (9-fluorenylmethoxy-carbonyl) chemistry to obtain peptides in high yield and purity is discussed. Peptide Synthesis Peptides were synthesized manually by solid phase method by stepwise coupling of Fmoc-amino acids to the growing chain on a Rink amide resin (0.9–1.1 mmol/g, Figures 1 and 3 for Desmopressin and Oxytocin) and 2-chlorotrityl chloride resin (Figure 2, for Octreotide). Detection of Secondary Amines on Solid-Phase. Chan Download Fmoc Solid Phase Peptide Synthesis: A Practical Approach C. Amino Groups in Solid-Phase Synthesis of Peptides. As thousands of individuals worldwide become involved with the study of peptides, and the demand for synthetic peptides rapidly increases, so too does the need for a practical, single-volume treatment of this growing field. Fmoc Solid Phase Peptide Synthesis: A Practical Approach. Oxford University Press., (2000). Publisher: Oxford University Press, USA Page Count: 376. Fmoc Solid Phase Peptide Synthesis: A Practical Approach ebook . The efficient solid-phase peptide synthesis of a functionalized bis-peptide trimer utilizing a 'safety catch' cleavage procedure from HMBA resin is described. (2) Fmoc Solid Phase Peptide Synthesis: A Practical Approach (Practical download pdf ebook .

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